I have a combo skimmer but never had the diverter, so never saw for myself how that works. It was explained to me by my x-pool-guy. I deleted the drains in a remodel, so it's all a non issue now. Since I never had the diverter, my drains were never active, so I knew ahead of time deleting the drains would have no affect on anything. I also have a dedicated suction port, but I use an automated three-way back at the pad to control flow between skimmer and vacuum, to optimize both. So in answer to the OP, no, I don't use a bottom drain, never did, and now that it's gone I don't miss it.
I suppose I have given up the safety option of a float valve, that would protect my pump. But since I never had that either, I don't miss that either. That issue is somewhat covered by my autofill system, which keeps the water level from dropping. I suppose other scenarios could occur to defeat that (like if the autofill stopped working), but I chose to take that risk to rid myself of the drains. A lot would have to go wrong: I'd be away for several days at the same time the autofill failed during the high-evaporation season. Not at all farfetched, but very slim possibility. If I was really concerned, a web cam on my pool (which is in the works) and my automation would be a third fail safe. If I saw the water dropping, I could just shut down the pump and call somebody.